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January 30, 2012

February 1, 2012

Dr’s are leaning towards an "undifferentiated Sarcoma" basically meaning they don't know where it came from but its not the obvious sarcoma cancers. A Dr. at St. Judes who is speaking with Brennan’s Dr. claims to never have seen a child with NB switch to this cancer.. so Brennan is a rare case.. Cindy has contacted the Sarcoma dept at Sloan-Kettering.. She just doesn't believe Brennan is the only child to deal with this.

After 9 painful days of waiting Brennan now has a diagnosis. This tumor is now diagnosed as Highly Aggressive secondary tumor of Undifferentiated Sarcoma. .

The two Chemo drugs Brennan will start sometime in the middle of the night are Ifosfamide and Doxirubicin.. At high doses.. much higher than his previous induction cycle for Neuroblastoma. His Ifosfamide previously was given at 300mg.. It is now  1,470mg.. his Dox was 4mg, and is now 18mg.. both of these are very harsh, especially at high doses. Brennan will have a heart ultrasound before each cycle is to be given because Dox is very damaging to the heart. Ifosfamide can at high doses cause acute neurological problems like seizures, extreme sedation and some others..

February 2, 2012

Chemo starts around noon today..

February 4, 2012

Since his blood pressure dropped it can either be chemo effect, which is very soon or just that they have diluted his blood with all the hydration he's been getting last several days. He's going to get blood and as long as he doesn't worsen he will be ok.. they say his bowel isn't obstructed all the way so an NG tube right now won't really help him much. So its a wait and see, hope he gets better type of thing. Until then he's on stronger doses of morphine and we're going to start our last day of chemo in a couple of hrs.


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Today 46 children will be diagnosed with some form of cancer, Today 7 children will DIE from  cancer!